Centro Andaluz de Biología Molecular y Medicina Regenerativa

Publications

/Publications
Selected publications in 2022:

  1. Benoit R Gauthier , Diana Rubio-Contreras , Juan Carlos Gómez-Rosado , Luis Cristobal Capitán-Morales , Abdelkrim Hmadcha, Bernat Soria, Christian Claude Lachaud. 2022. Human Omental Mesothelial Cells Impart an Immunomodulatory Landscape Impeding B- and T-Cell Activation. Int J Mol Sci. 3(11):5924.

  2. Blessing C, Apelt K, van den Heuvel D, Gonzalez-Leal C, Rother MB, van der Woude M, González-Prieto R, Yifrach A, Parnas A, Shah RG, Kuo TT, Boer DEC, Cai J, Kragten A, Kim HS, Schärer OD, Vertegaal ACO, Shah GM, Adar S, Lans H, van Attikum H, Ladurner AG, Luijsterburg MS. 2022. XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair. Nat Commun. 13(1):4762.

  3. Bodineau C, Tomé M, Murdoch PDS, Durán RV. 2022. Glutamine, MTOR and autophagy: a multiconnection relationship. Autophagy (Review). Ahead of print .

  4. Bruxel MA, da Silva FN, da Silva RA, Zimath PL, Rojas A, Moreira ELG, Quesada I, Rafacho A. 2022. Preconception exposure to malathion and glucose homeostasis in rats: Effects on dams during pregnancy and post-term periods, and on their progeny. Environ Pollut. 316(Pt 2):120633..

  5. Caballano-Infantes E, Cahuana GM, Bedoya FJ, Salguero-Aranda C, Tejedo JR. 2022. The Role of Nitric Oxide in Stem Cell Biology. Antioxidants (Basel). 11(3):497 .

  6. Cañas JC, García-Rubio ML, García A, Antequera F, Gómez-González B, Aguilera A. 2022. A role for the Saccharomyces cerevisiae Rtt109 histone acetyltransferase in R-loop homeostasis and associated genome instability. Genetics. Online ahead of print.

  7. Castañé A, Riga MS, Cano M, Ruiz-Avila L, Miquel-Rio L, Celada P, Artigas F. 2022. The dual 5-HT3 and 5-HT6 receptor antagonist FPPQ normalizes phencyclidine-induced disruption of brain oscillatory activity in rats. Int J Neuropsychopharmacol. 25(5):425-431 .

  8. Delgado-Chaves FM, Martínez-García PM, Herrero-Ruiz A, Gómez-Vela F, Divina F, Jimeno-González S, Cortés-Ledesma F. 2022. Data of transcriptional effects of the merbarone-mediated inhibition of TOP2. Data Brief. 44:108499.

  9. Gallardo-Chamizo F, Lara-Ureña N, Correa-Vázquez JF, Reyes JC, Gauthier BR, García-Domínguez M. 2022. SENP7 overexpression protects cancer cells from oxygen and glucose deprivation and associates with poor prognosis in colon cancer. Genes Dis. 9(6):1419-1422..

  10. Gallego-Durán R, Albillos A, Ampuero J, Arechederra M, Bañares R, Blas-García A, Berná G, Caparrós E, Delgado TC, Falcón-Pérez JM, Francés R, Fernández-Barrena MG, Graupera I, Iruzubieta P, Nevzorova YA, Nogueiras R, Macías RI, Marín F, Sabio G, Soriano G, Vaquero J, Cubero FJ, Gracia-Sancho J. 2022. Metabolic-associated fatty liver disease: from simple steatosis towards liver cirrhosis and potential complications Proceedings of the Third Translational Hepatology Meeting, endorsed by the Spanish Association for the Study of the Liver (AEEH). Gastroenterol Hepatol. S0210-5705(22)00079-6. .

  11. Gallego-Durán R, Albillos A, Ampuero J, Arechederra M, Bañares R, Blas-García A, Berná G, Caparrós E, Delgado TC, Falcón-Pérez JM, Francés R, Fernández-Barrena MG, Graupera I, Iruzubieta P, Nevzorova YA, Nogueiras R, Macías RIR, Martín F, Sabio G, Soriano G, Vaquero J, Cubero FJ, Gracia-Sancho J. 2022. Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications Proceedings of the Third Translational Hepatology Meeting, organized by the Spanish Association for the Study of the Liver (AEEH). J GASTROENTEROL Hepatology. 45(9):724-734..

  12. Gallego-Durán R, Ampuero J, Pastor-Ramírez H, Álvarez-Amor L, Del Campo JA, Maya-Miles D, Montero-Vallejo R, Cárdenas-García A, Pareja MJ, Gato-Zambrano S, Millán R, Del Carmen Rico M, Luque-Sierra A, Gil-Gómez A, Rojas Á, Muñoz-Hernández R, García-Lozano M, Aller R, Andrade RJ, García-Monzón C, Andreola F, Martín F, Jalan R, Romero-Gómez M. 2022. Liver injury in non-alcoholic fatty liver disease is associated with urea cycle enzyme dysregulation. Sci Rep. 12(1):3418 .

  13. Garcia-Dominguez M. 2022. Proper progression of neurogenesis relies on a defined pattern of SUMO-modified proteins. Neural Regen Res. 17(8):1731-1732 .

  14. García-Gutiérrez P, García-Domínguez M. 2022. SUMO control of nervous system development. Semin Cell Dev Biol. Ahead of Print.

  15. García-Rodríguez N, Manzano-López J, Muñoz-Bravo M, Fernández-García E, Muñiz M, Wellinger RE. 2022. Manganese redistribution by calcium-stimulated vesicle trafficking bypasses the need for P-type ATPase function. J Biol Chem. 290(15):9335-47.

  16. Gómez-Marín E, Posavec-Marjanovi? M, Zarzuela L, Basurto-Cayuela L, Guerrero-Martínez JA, Arribas G, Yerbes R, Ceballos-Chávez M, Rodríguez-Paredes M, Tomé M, Durán RV, Buschbeck M, Reyes JC. 2022. The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGF? and Hippo pathways. Nucleic Acid RES. .

  17. González-Arzola K, Díaz-Quintana A, Bernardo-García N, Martínez-Fábregas J, Rivero-Rodríguez F, Casado-Combreras MÁ, Elena-Real CA, Velázquez-Cruz A, Gil-Caballero S, Velázquez-Campoy A, Szulc E, Gavilán MP, Ayala I, Arranz R, Ríos RM, Salvatella X, Valpuesta JM, Hermoso JA, De la Rosa MA, Díaz-Moreno I. 2022. Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid-liquid phase separation. Nat Struct Mol Biol. 29(10):1024-1036.

  18. González-Garrido C, Prado F. 2022. Novel insights into the roles of Cdc7 in response to replication stress. FEBS J. 290(12):3076-3088.

  19. González-Mariscal I, Pozo Morales M, Romero-Zerbo SY, Espinosa-Jimenez V, Escamilla-Sánchez A, Sánchez-Salido L, Cobo-Vuilleumier N, Gauthier BR, Bermúdez-Silva FJ. 2022. Abnormal cannabidiol ameliorates inflammation preserving pancreatic beta cells in mouse models of experimental type 1 diabetes and beta cell damage. Biomed Pharmacother. 145:112361 .

  20. González-Sánchez Z, Areal-Quecuty V, Jimenez-Guerra A, Cabanillas-Balsera D, Gil FJ, Velasco-Ortega E, Pozo D. 2022. Titanium Surface Characteristics Induce the Specific Reprogramming of Toll-like Receptor Signaling in Macrophages. Int J Mol Sci. 23(8):4285 .

  21. Han SS, Wen KK, García-Rubio ML, Wold MS, Aguilera A, Niedzwiedz W, Vyas YM. 2022. WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage. Nat Commun. 13(1):3743.

  22. Lara-Ureña N, Jafari V, García-Domínguez M. 2022. Cancer-Associated Dysregulation of Sumo Regulators: Proteases and Ligases. Int J Mol Sci . .

  23. López-Bermudo L, Luque-Sierra A, Maya-Miles D, Gallego-Durán R, Ampuero J, Romero-Gómez M, Berná G, Martín F. 2022. Contribution of Liver and Pancreatic Islet Crosstalk to ?-Cell Function/Dysfunction in the Presence of Fatty Liver. Front Endocrinol (Lausanne). 13:892672 .

  24. López-Jiménez E; González-Aguilera C. 2022. Role of Chromatin Replication in Transcriptional Plasticity, Cell Differentiation and Disease. GENES. 13(6):1002..

  25. López-Terrones E, Celada P, Riga MS, Artigas F. 2022. Preferential In Vivo Inhibitory Action of Serotonin in Rat Infralimbic versus Prelimbic Cortex: Relevance for Antidepressant Treatments. Cereb Cortex. 32(14):3000-3013.

  26. Martin Vázquez E, Cobo-Vuilleumier N, Araujo Legido R, Marín-Cañas S, Nola E, Dorronsoro A, López Bermudo L, Crespo A, Romero-Zerbo SY, García-Fernández M, Martin Montalvo A, Rojas A, Comaills V, Bérmudez-Silva FJ, Gannon M, Martin F, Eizirik D, Lorenzo PI, Gauthier BR. 2022. NR5A2/LRH-1 regulates the PTGS2-PGE 2-PTGER1 pathway contributing to pancreatic islet survival and function. Iscience. 25(5):104345 .

  27. Martínez-García MÁ, Sierra-Párraga JM, Garcia-Ortega A A. 2022. Obstructive sleep apnea in women: We can do more and better. Sleep Med Rev. 64:101645.

  28. Martinez-Garcia MA, Sierra-Párraga JM, Quintana E, López-Campos JL. 2022. CFTR dysfunction and targeted therapies: A vision from non-cystic fibrosis bronchiectasis and COPD. J Cyst Fibros. 1569-1993(22)00107-2.

  29. Mayoral I, Bevilacqua E, Gómez G, Hmadcha A, González-Loscertales I, Reina E, Sotelo J, Domínguez A, Pérez-Alcántara P, Smani Y, González-Puertas P, Mendez A, Uribe S, Smani T, Ordoñez A, Valverde I. 2022. Tissue engineered in-vitro vascular patch fabrication using hybrid 3D printing and electrospinning. Mater Today Bio. 14:100292 .

  30. Millán-Zambrano G, Burton A, Bannister AJ, Schneider R. 2022. Histone post-translational modifications - cause and consequence of genome function. Nat Rev Genet. Ahead of print .

  31. Mora-Molina R and Lopez-Rivas A. 2022. Restoring TRAILR2/DR5-Mediated Activation of Apoptosis upon Endoplasmic Reticulum Stress as a Therapeutic Strategy in Cancer. Int J Mol Sci. .

  32. Mora-Molina R, Stöhr D, Rehm M, López-Rivas A. 2022. cFLIP downregulation is an early event required for endoplasmic reticulum stress-induced apoptosis in tumor cells. Cell Death Dis. 13(2):111 .

  33. Olmedo-Moreno L, Aguilera Y, Baliña-Sánchez C, Martín-Montalvo A, Capilla-González V. 2022. Heterogeneity of In Vitro Expanded Mesenchymal Stromal Cells and Strategies to Improve Their Therapeutic Actions. Pharmaceutics. 14(5):1112 .

  34. Peña-Gómez MJ, Moreno-Gordillo P, Narmont? M, García-Calderón CB, Ruk??nait? A, Klima?auskas S, Rosado IV. 2022. FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2'-deoxycytidine and 5-hydroxymethyl-2'-deoxyuridine. Cell Death Dis. 13(5):503 .

  35. Peña-Gómez MJ, Suárez-Pizarro M, Rosado IV. 2022. XRCC1 Prevents Replication Fork Instability during Misincorporation of the DNA Demethylation Bases. Int J Mol Sci. 14;23(2):893 .

  36. Pladevall-Morera D, Castejón-Griñán M, Aguilera P, Gaardahl K, Ingham A, Brosnan-Cashman JA, Meeker AK, Lopez-Contreras AJ. 2022. ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors. Cancers (Basel). 14(7):1790 .

  37. Polo-Generelo S, Torres B, Guerrero-Martínez JA, Camafeita E, Vázquez J, Reyes JC, Pintor-Toro JA. 2022. TGF-?-Upregulated Lnc-Nr6a1 Acts as a Reservoir of miR-181 and Mediates Assembly of a Glycolytic Complex. Noncoding RNA. 8(5):62.

  38. Ravoityt? B, Luk?a J, Wellinger RE, Serva S, Servien? E. 2022. Adaptive Response of Saccharomyces Hosts to Totiviridae L-A dsRNA Viruses Is Achieved through Intrinsically Balanced Action of Targeted Transcription Factors. J Fungi (Basel). 8(4):381 .

  39. Romero-Gómez M, Aller R, Martín-Bermudo F. 2022. Dietary Recommendations for the Management of Non-alcoholic Fatty Liver Disease (NAFLD): A Nutritional Geometry Perspective. Semin Liver Dis.  Online ahead of print..

  40. Sakellariou D, Bak ST, Isik E, Barroso SI, Porro A, Aguilera A, Bartek J, Janscak P, Peña-Diaz J. 2022. MutS? regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells. Cell Rep. 39(1):110602 .

  41. Salas-Lloret D, González-Prieto R. 2022. Insights in Post-Translational Modifications: Ubiquitin and SUMO. Int J Mol Sci. 23(6):3281 .

  42. Salguero-Aranda C, Beltran-Povea A, Postigo-Corrales F, Hitos AB, Díaz I, Caballano-Infantes E, Fraga MF, Hmadcha A, Martín F, Soria B, Tapia-Limonchi R, Bedoya FJ, Tejedo JR, Cahuana GM. 2022. Pdx1 Is Transcriptionally Regulated by EGR-1 during Nitric Oxide-Induced Endoderm Differentiation of Mouse Embryonic Stem Cells. Int J Mol Sci. 23(7):3920 .

  43. Sánchez-Escabias E, Guerrero-Martínez JA, Reyes JC. 2022. Co-transcriptional splicing efficiency is a gene-specific feature that can be regulated by TGF. Commun Biol. 5(1):277 .

  44. Sarmiento A, Durán-Díaz I, Fondón I, Tomé M, Bodineau C, Durán RV. 2022. A Method for Unsupervised Semi-Quantification of Inmunohistochemical Staining with Beta Divergences. Entropy (Basel). 24(4):546 .

  45. Sarni D, Barroso S, Shtrikman A, Irony-Tur Sinai M, Oren YS, Aguilera A, Kerem B. 2022. Topoisomerase 1-dependent R-loop deficiency drives accelerated replication and genomic instability. Cell Rep. 40(13):111397.

  46. Tessier S, Ferhi O, Geoffroy MC, González-Prieto R, Canat A, Quentin S, Pla M, Niwa-Kawakita M, Bercier P, Rérolle D, Therizols P, Fabre E, Vertegaal ACO, de Thé H, Lallemand-Breitenbach V. 2022. Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells. Nat Commun. 13(1):5726.

  47. Valdés-Sánchez L, Borrego-González S, Montero-Sánchez A, Massalini S, de la Cerda B, Díaz-Cuenca A, Díaz-Corrales FJ. 2022. Mesoporous Silica-Based Nanoparticles as Non-Viral Gene Delivery Platform for Treating Retinitis Pigmentosa. J Clin Med. 11(8):2170 .

  48. Wellinger RE, Aguilar-Ruiz JS. 2022. A new challenge for data analytics: transposons. BioData Min. 15(1):9 .

  49. Yerbes R, Mora-Molina R, Fernández-Farrán FJ, Hiraldo L, López-Rivas A, Palacios C. 2022. Limiting glutamine utilization activates a GCN2/TRAIL-R2/Caspase-8 apoptotic pathway in glutamine-addicted tumor cells. Cell Death Dis. 27;13(10):906.