Centro Andaluz de Biología Molecular y Medicina Regenerativa

Publications

/Publications
Selected publications in 2012:

  1. Aguilera A, García-Muse T. 2012. R Loops: From Transcription Byproducts to Threats to Genome Stability. Mol Cell. 46:115-124.

  2. Bedoya FJ, Salguero-Aranda C, Cahuana GM, Tapia-Limonchi R, Soria B, Tejedo JR. 2012. Regulation of pancreatic b-cell survival by nitric oxide: clinical relevance. Islets. 4(2):108-18.

  3. Carrasco M, Delgado I, Soria B, Martín F, Rojas A. 2012. GATA4 and GATA6 control mouse pancreas organogenesis. J Clin Invest. 122(10):3504-15.

  4. Castellano-Pozo M, García-Muse T, Aguilera A. 2012. The Caenorhabditis elegans THO complex is required for the mitotic cell cycle and development. PLoS One. 7(12):e52447.

  5. Castellano-Pozo M, García-Muse T, Aguilera A. 2012. R-loops cause replication impairment and genome instability during meiosis. EMBO Rep. 13(10):923-9.

  6. Ceballos-Chávez M, Rivero S, García-Gutiérrez P, Rodríguez-Paredes M, García-Domínguez M, Bhattacharya S, Reyes JC. 2012. Control of neuronal differentiation by sumoylation BRAF35, a subunit of the LSD1-CoREST histone demethylase complex. Proc Natl Acad Sci U S A. (21):8085-90 .

  7. Cejudo-Guillén M, Ramiro-Gutiérrez ML, Labrador-Garrido A, Díaz-Cuenca A, Pozo D. 2012. Nanoporous silica microparticle interaction with toll-like receptor agonists in macrophages. Acta Biomater. PMID: 22842032 .

  8. Clemente-Ruiz M, Prado F. 2012. Nucleosome assembly and genome integrity. BioArchitecture. 2( 1): 6-10.

  9. Cobo-Vuilleumier N, Gauthier BR. 2012. PARP-1 and cytokine-mediated ?-cell damage: a nick in the Okamoto model?. Am J Physiol Endocrinol Metab. 303(2):E170-1.

  10. Erceg S, Lukovic D, Moreno-Manzano V, Stojkovic M, Bhattacharya SS. 2012. Derivation of cerebellar neurons from human pluripotent stem cells. Curr Protoc Stem Cell Biol. PMID:22415839.

  11. Ferrándiz N, Caraballo JM, García-Gutierrez L, Devgan V, Rodriguez-Paredes M, Lafita MC, Bretones G, Quintanilla A, Muñoz-Alonso MJ, Blanco R, Reyes JC, Agell N, Delgado MD, Dotto GP, León J. 2012. p21 is a co-repressor of cyclin E2 and mitotic control genes. Plos One. 7(5):e37759 .

  12. Gálvez P, Clares B, Hmadcha A, Ruiz A, Soria B. 2012. Development of a cell-based medicinal product: regulatory structures in the European Union. Br Med Bull. 105:85-105.

  13. Garcia-Gutierrez P, Mundi M, Garcia-Dominguez M. 2012. Association of bromodomain BET proteins with chromatin requires dimerization through the conserved motif B. J Cell Sci. 125(Pt 15):3671-80.

  14. García-Rodríguez N, Díaz de la Loza Mdel C, Andreson B, Monje-Casas F, Rothstein R, Wellinger RE. 2012. Impaired manganese metabolism causes mitotic misregulation. J Biol Chem. 287(22):18717-29.

  15. García-Rubio ML, Aguilera A. 2012. Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes. Nucleic Acids Res. 40(3):1050-64.

  16. Kamenarova K, Cherninkova S, Romero Durán M, Prescott D, Valdés Sánchez ML, Mitev V, Kremensky I, Kaneva R, Bhattacharya SS, Tournev I, Chakarova C. 2012. A novel locus for autosomal dominant cone-rod dystrophy maps to chromosome 10q. Eur J Hum Genet. doi: 10.1038/ejhg.2012.158.

  17. Lukovic D, Moreno-Manzano V, Stojkovic M, Bhattacharya SS, Erceg S. 2012. Human pluripotent Stem Cells in the Treatment of Spinal Cord Injury. Stem Cells. 30(9):1787-92.

  18. Luna R, Rondón AG, Aguilera A. 2012. New clues to understand the role of THO and other functionally related factors in mRNP biogenesis. Biochim Biophys Acta. 1819(6):514-20 .

  19. Mannini B, Cascella R, Zampagni M, van Waarde-Verhagen M, Meehan S, Roodveldt C, Campioni S, Boninsegna M, Penco A, Relini A, Kampinga HH, Dobson CM, Wilson MR, Cecchi C, Chiti F. 2012. Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers. Proc Natl Acad Sci USA. doi: 10.1073/pnas.1117799109.

  20. Martín M, Menéndez P. 2012. Biological impact of human embryonic stem cells. Adv Exp Med Biol. 741:217-30.

  21. Martín-Pérez R, Niwa M, López-Rivas A. 2012. ER stress sensitizes cells to TRAIL through down-regulation of FLIP and Mcl-1 and PERK-dependent up-regulation of TRAIL-R2. Apoptosis. 17(4):349-63.

  22. Mellado-Gil JM, Cobo-Vuilleumier N, Gauthier BR. 2012. Islet Beta-cell Mass Preservation and Regeneration in Diabetes Mellitus: Four Factors with Potential Therapeutic Interest. Journal of Transplantation. 2012:230870.

  23. Muñoz-Galván S, López-Saavedra A, Jackson SP, Huertas P, Cortés-Ledesma F, Aguilera A. 2012. Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination. Nucleic Acids Res. 41(3):1669-83.

  24. Muñoz-Galván S, Tous C, Blanco MG, Schwartz EK, Ehmsen KT, West SC, Heyer WD, Aguilera A. 2012. Distinct roles of mus81, yen1, slx1-slx4, and rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange. Mol Cell Biol. 32:1592-1603.

  25. Pardo B, Aguilera A. 2012. Complex chromosomal rearrangements mediated by break-induced replication involve structure-selective endonucleases. PLoS Genet. 8(9):e1002979.

  26. Peña A, Gewartowski K, Mroczek S, Cuéllar J, Szykowska A, Prokop A, Czarnocki-Cieciura M, Piwowarski J, Tous C, Aguilera A, Carrascosa JL, Valpuesta JM, Dziembowski A. 2012. Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor. EMBO J. 31(6):1605-16.

  27. Rodríguez-Jimnez FJ, Alastrue-Agudo A, Erceg S, Stojkovic M, Moreno-Manzano V. 2012. FM19G11 favors spinal cord injury regeneration and stem cell self-renewal by mitochondrial uncoupling and glucose metabolism induction. Stem Cells. 30(10):2221-33.

  28. Rodriguez-Vargas JM, Ruiz-Magaña MJ, Ruiz-Ruiz C, Muñoz-Gámez JA, Siles A, Lopez-Rivas A, Jaatela M, Oliver FJ. 2012. ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy. Cell Research. doi: 10.1038/cr.2012.70 .

  29. Soria B, Navas S, Hmadcha A, Hamill OP. 2012. Single Mechanosensitive and Ca(2+)-Sensitive Channel Currents Recorded from Mouse and Human Embryonic Stem Cells. J Membr Biol. 246(3):215-30.

  30. Volarevic V, Erceg S, Bhattacharya SS, Stojkovic P, Horner P, Stojkovic M. 2012. Stem cell based therapy for spinal cord injury. Cell Transplant. 22(8):1309-23.

  31. Yerbes R, López-Rivas A, Reginato MJ, Palacios C. 2012. Control of FLIPL expression and TRAIL resistance by the extracellular signal-regulated kinase (ERK)1/2 pathway in breast epithelial cells. Cell Death Differ. doi: 10.1038/cdd.2012.78. [ .

  32. Yerbes R, López-Rivas A. 2012. Itch/AIP4-independent proteasomal degradation of cFLIP induced by the histone deacetylase inhibitor SAHA sensitizes breast tumour cells to TRAIL. Invest New Drugs. 30(2):541-7.