Selected Publications
J Exp Clin Cancer Res Radiotherapy resistance driven by Asparagine endopeptidase through ATR pathway modulation in breast cancer.
Surv Ophthalmol Pharmacological agents for treatment of proliferative vitreoretinopathy: A systematic review and network meta-analysis.
Science advances HMCES corrupts replication fork stability during base excision repair in homologous recombination-deficient cells.
Staff
Tatiana García Muse
DNA damage response during meiosis
Genomic DNA is under constant attack from both endogenous and exogenous DNA damaging agents. Without proper repair the resulting DNA damages would lead to alteration of genomic structure thus affecting the faithful transmission of genetic information. In addition, defects during meiosis lead to aneuploidy, an extreme kind of genetic instability associated with fertility problems, miscarriages and mental retardation syndromes. I use the Caenorhabditis elegans model organism to address the impact of DNA damage on genome stability in meiotic cells.
Seminars
- 25 April 2025
Seminario
Kristine Freude – The increased risk of Alzheimer’s disease in women is influenced by the interplay of genetic risk factors, sex, and age
