Xosé J. Bustelo
Role of Vav oncoproteins in cancer: from mice to humans and viceversa
Andre Nussenzweig
Genome Organization Drives Chromosome Fragility
Joaquín Dopazo
Pathway activity models as precision diagnostic and prognostic biomarkers linked to cell function that uncover disease mechanisms
Kathrin Maedler
Save the β-cell! A bench-to-bed approach for diabetes
Dr. Pablo Huertas
How to fix a broken chromosome
Dr. Acaimo González Reyes
ECM remodelling in the stem cell niche: lessons form the Drosophila ovary
Dr. Lourdes Serrano
SirT7 as Safeguard of Genome Integrity
Dra. Purificación Muñoz
Understanding muscle stem cell regenerative decline with aging
Dra. Nuria López-Bigas
Tumor genomes shed light into somatic mutational processes and cancer vulnerabilities
Dr. Mathieu Gerard
Genome-wide nucleosome specificity and function of chromatin remodelers in embryonic stem cells
Dr. Angel Raya
Reprogramming somatic cell fate and identity: Biomedical applications
Dr. Jiri Lukas
Endogenous DNA damage: How cells deal with unavoidable
Dra. Gaelle Legube
Chromosome and chromatin dynamics during DNA Double Strand Break repair
Dr. Martí Aldea
Molecular competition and cell size control: a link to cell ageing?
Dr. Angel Nadal
Endocrine disruptors and insulin resistance: is hyperinsulinemia cause or consequence?
Dr. Pedro Herrera
Beta-cell reconstitution by islet cell-type interconversion
Dr. Dan Durocher
Charting the response to DNA double-strand breaks
Dra. Mª Luz López Rodríguez
Chemistry for drug target validation and identification
Dra. María Gómez
Dynamic Interplay between chromatin structure, DNA replication and transcription elongation to maintain genome stability
Dr. Ralf Wellinger
Origin-independent replication priming
Prof. Johannes M. Herrmann
Protein oxidation in mitochondria
Dr. Yossi Shiloh
The DNA damage response, between genome stability and cellular homeostasis, between bench and bedside
Dr. Felipe Cortés
Topoisomerase-blocked DNA breaks
Dr. José A. Tercero
Coping with DNA damage during chromosome replication
Dr. Ben Lehner
Genotype is not everything: transgenerational epigenetic memory in worms and somatic mutations in tumours
Dr. Alessandro Sartori
Regulation of DNA-end resection by CtIP modification
Dr. Matt Neale
Spatial patterning of recombination by DNA damage response checkpoint kinases
Dr. Haikun Liu
Molecular control of self-renewal and differentiation in neural stem cells and brain tumors
Prof. Pedro Lazo
Implication of the VRK1 chromatin kinase in the cellular responses to DNA
Prof. Lucy Walker
Immune regulatory mechanisms in type 1 diabetes
Dra. Anne Grapin-Botton
Individual cell contributions to pancreas organogenesis: stochasticity, heterogeneity and self organization
Dr. Anand Swaroop
Gene Regulatory Networks Guiding Photoreceptor Development and Disease
Prof. Luis Aragón
Topoisomerase II intertwines sister chromatids post-replication at cohesion sites
Prof. Alberto Pendás
Functional analysis of the cohesin
complexes in mammalian reproduction
Prof. Erik Boye
Translation and cell-cycle transitions
Dra. Anabel Rojas
GATA factors in pancreas and liver
development and disease
Félix Prado
Chromatin assembly in genome integrity and cell cycle progression
Oscar Llorca
Molecular and structural understanding of DNA repair using 3D-Electron Microscopy
Dr. Lucia Tabares
Synaptic dysfunctions in motor neurons
diseases
Sandra Peiró
Chromatin dynamics in epithelial-mesenchymal transition (EMT)
Pr. Hemant Khanna
Cone Photoreceptor pathogenesis in
retinitis pigmentosa
Vincenzo Costanzo
DNA replication and genome stability maintenance: novel molecular insights using a vertebrate cell free system
Dra. Natalia Tapia
Mechanisms underlying somatic reprogramming
Fabrizio Chiti
The determinants of protein oligomer toxicity
Alberto Pendás
Functional analysis of the cohesin complexes in mammalian reproduction
Fernando Moreno Herrero
Single-molecule approaches to study double-stranded DNA break resection
Patrick Collombat
Inducing alpha-cell-mediated beta-like cell neogenesis
Adele Marston
Orienting chromosomes in mitosis and meiosis
Michael lisby
Maintaining genome integrity through mitosis
Hannah Klein
Consequences of ribonucleotides in DNA
Rodrigo Bermejo
Mechanisms of replication fork monitoring and protection
Prof. Abelardo López Rivas
Competing networks in cell fate decisions: the TRAIL system
Dr. Benoit R. Gauthier
Harnessing the regenerative potential of pancreatic islet cells as treatment for Diabetes Mellitus
Dr. Patrick Charnay
Peripheral nervous system stem cells
Dr. Tony Carr
Mechanisms and consequences of replication fork collapse and restart
Dr. Brian Black
Transcriptional regulation of outflow tract morphogenesis
Dr. Marco Milán
CIN-induced tumorigenesis in Drosophila
Dr. Gislene Pereira
Coordination of chromosome segregation with cell division
Dr. Fernando Martin-Belmonte
Acquisition of cell polarity in 3D environments
Dr. Francisco Real
Pancreatic cancer: does differentiation set the stage for inflammation and carcinogenesis?
Dr. Philippe Pasero
Cellular responses to spontaneous replication stress
Dr. Balbino Alarcón
Clustering, conformational changes and cooperativity in the T-cell receptor
Dr. Oskar Fernandez-Capetillo
Exploring the roles of replicative stress in cancer and ageing
Dr. Marian martínez-Balbás
Histone demethylases: new regulators of nervous system development
Dr. Francisco Antequera
Nucleosomal organization and evolution of the eukaryotic genome
Prof. Maureen Gannon
Factors Promoting Pancreatic Beta Cell Replication and Regeneration
Prof. Travis Stracker
Understanding the DNA damage response in human disease
Prof. Shomi Bhattacharya
Retinitis Pigmentosa: Light at the end of the tunnel?
D. Michelle Debatisse
Common fragile sites: mechanism of activation and impact on chromosome instability in cancers
Dr. Simón Méndez Ferrer
Neuroendocrine regulation of the stem cell niche as a therapeutic target
Prof. Kinichi Nakashima
Treatment of spinal cord injury by transplantation of neural stem cells
Maria Dominguez, Ph.D.
Symmetry, proportions, and accuracy in size control: role of Drosophila insulin-like peptide 8
D. Giacomo Cavalli
Polycomb proteins in nuclear organisation and developmental regulation in Drosophila
Dr. Karim Labib
Controlling genome integrity via post-translational regulation of the eukaryotic replisome
Dr. Ana Losada
Mouse models to investigate cohesin functions
Dr. Jose Luis García Pérez
LINE-1 retrotransposition in Fanconi Anemia patients
Prof. Jose Manuel Cuezva Marcos
The mitochondrial H+-ATP synthase-geared switch of metabolism in human tumors
Prof. Laszlo Tora
Transcription, replication, chromosomal common fragile site instability and the characterization of the human TREX-2 complex
Prof. Isabel Fariñas
Neural stem cells: life at home
Dr. Francisco Javier Bermúdez Silva
Cannabinoid receptors signalling in the islets of Langerhans. Involvement in the pathophysiology of type 2 diabetes.
Luis María Escudero Cuadrado
Characterization of biological images through network analysis
Prof. M. Pia Cosma
Dissecting mechanisms controlling somatic cell reprogramming and tissue regeneration
Prof. Ginés Morata
Cell competition and tumour development in Drosophila
Prof.Juan Jiménez
Nucleocytoplasmic transport in the midzone membrane domain controls mitotic spindle disassembly
Prof. Moshe Yaniv
From oncogenic viruses to chromatin and cancer
Prof. Jesper Q. Svejstrup
Transcription and its interface with other DNA-related processes
Prof. Jan H. Hoeijmakers
Genome stability: impact on cancer, aging and longevity
Prof. J. Antonio Enríquez
Why do we not understand the impairment of oxidative phosphorylation system
Prof. Marisol Soengas
Understanding and Treating Malignant Melanoma
Prof. Andre Nussenzweig
Interplay between pathways that maintain genome stability
Prof. Jose L. Gómez Skarmeta
Enhancer dynamics during vertebrate development and its influence on the genomic architecture
Prof. Romano Regazzi
Emerging roles of microRNAs in the control of pancreatic beta cell functions
Prof. Alberto R. Kornblihtt
Chromatin and transcription regulate alternative splicing
Prof. Luciano Di Croce
The impact of histone modifications and chromatin alterations on gene expression, stem cell differentiation and cancer
Prof. Jesper Svejstrup
The interface between transcription and the maintenance of genome integrity
Prof. Wolf-Dietrich Heyer
Mechanisms of homologous recombination: Controlling the assembly of the Rad51-ssDNA filament
Prof. Francesc Posas
Responses to stress mediated by SAPKS
Prof. Marcos González- Gaitán
Sara endosomes and asymmetric cell division
Prof. Catherine Dargemont
Ubiquitin and coordination of mRNA biogenesis
Prof. Simon Boulton
Controlling recombination
Prof. Sergio Moreno
Cell cycle exit, cell differentiation and cancer
Prof. Francisco Baralle
From pre-mRNA splicing to neurodegeneration, a new role for the hnRNP TDP 43
Prof. Howard Riezman
Lipid Metabolism and Function in Model Organisms and Cells
Prof. Manel Esteller
Epigenetics in Health and Disease
Prof. Roger Pedersen
Mechanisms of pluripotency and differentiation in mammalian embryonic stem cells
Prof. María Blasco
Role of telomeres and telomerase in cancer and aging
Prof. Francisco Sánchez-Madrid
Mechanisms of intercellular communication in the immune response
Prof. Ashok Bhagwat
Controlled Harm is Good for You...
Prof. Miguel Beato
Towards an integrated view of progesterone action in breast cancer cells
Dr. Ketan J. Patel
The Fanconi Anaemia DNA Repair Pathway
Dr. Jorge Ferrer
Plasticity of pancreatic duct cells
Prof. Ted Weinert
The wild world of genome instability in yeast: dicentrics, repeats, replication fork biology, cohesions
Prof. Keith Caldecott
DNA strand break repair and human genetic disease
Prof. Claes Wollheim
Beta cell mitochondrial signals determine glucose-stimulated insulin secretion
Dr. Joaquín Gómez
Aplicaciones Biomédicas del CNA
Prof. Tony Kouzarides
Chromatin Modifying Enzymes: their function and role in cancer
Prof. Alan Lehmann
Replication of damaged DNA, translesion synthesis and cancer avoidance
Prof. FrançoisMajor
New tools for RNA structure prediction and their applications...
Prof. Andrea Ballabio
A gene network regulating lysosomal biogenesis and function
Prof. Andrés Moya
The human microbiome: our first attempts
Prof. Erik Boye
Regulation of the G1/S transition. A coupling between cell growth and cell-cycle control?
Prof. Dan S. Tawfik
Protein evolution - a reconstructive approach
Prof. Paola Bovolenta
Beyond Wnt inhibition: multiple functions of secreted Frizzled-related proteins in eye and brain development
Prof. Ángela Nieto
Ancestral and derived roles of the Snail/Scratch superfamily in embryonic development and adult pathologies
Prof. Michael Neuberger
Antibody diversification through DNA deamination
Dr. Guillermo Montoya
Structural biology of homing endonucleases: from basics to therapeutics
Prof. Ana C. Carrera
PI3K as a pulling force for cell cycle progression
Prof. Ed Hurt
How ribonucleoprotein particles are formed and exported to the cytoplasm
Prof. Cayetano González
Neural Stem Cell polarity and malignant growth in Drosophila
Prof. Isabelle Vernos
The mechanism of bipolar spindle assembly: keeping the spindle in balance
Prof. Ferran Azorin
The regulation of chromatin functions
Prof. Danny Reinberg
A Molecular Understanding of Epigenetics
Dr. Manuel Serrano
Tumor suppressors in cancer, aging and reprogramming
Dr. Wolfgang Parak
Biological applications of colloidal nanoparticles-how nanotechnology can contribute to diagnosis and treatment
Prof. Jean Marc Egly
DNA repair and transcription, what we learned from the XP and TTD patients
Dra. Margarita Salas
Protein-primed replication of bacteriophage ø29 DNA
Dr. Madalena Tarsounas
Homologous recombination in genome stability and telomere maintenance
Luis Aragon
Topoisomerase II entwines sister chromatids at cohesin sites prior to anaphase
Debra J. Wolgemuth, Ph.D.
Role of the BET Family of Double Bromodomain Proteins in Development, Differentiation and Disease
Abelardo Lopez Rivas
Competing networks in cell fate decisions: the TRAIL system