Research Groups
Selected Publications
Nucleic Acids Res EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells.
Genes Dev RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity.
Brain Scn1a haploinsufficiency in the prefrontal cortex engages to cognitive impairment and depressive phenotype.
Staff
Ralf Erik Wellinger
Mitochondrial Plasticity and Replication
The genetic material including mitochondrial, telomeric and nucleolar (ribosomal) DNA is constantly exposed to endogenous or exogenous stress. We are particularly interested in the factors and molecular pathways causing genome instability, disease and premature aging.
Seminars
- 21 November 2024
Seminario
Yatin Vyas – DNA’s Cosmic Weapon : The Entangled Power of WASp and Fanconi Anemia in Replication - 29 November 2024
Seminario
Rosa Barrio – Control of proteostasis in development and rare diseases - 13 December 2024
Seminario
Guadalupe Sabio – From Beatsto Metabolism : Unveiling the Heart’s Metabolic Power