Research Groups
Selected Publications
Nucleic Acids Res EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells.
Genes Dev RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity.
Brain Scn1a haploinsufficiency in the prefrontal cortex engages to cognitive impairment and depressive phenotype.
Staff
Ralf Erik Wellinger
Mitochondrial Plasticity and Replication
The genetic material including mitochondrial, telomeric and nucleolar (ribosomal) DNA is constantly exposed to endogenous or exogenous stress. We are particularly interested in the factors and molecular pathways causing genome instability, disease and premature aging.
Seminars
- 17 January 2025
Seminario
Juan Méndez – Tolerating DNA damage by repriming: molecular mechanisms and opportunities for cancer therapy - 24 January 2025
Seminario
Teresa Rodríguez – Islet HLA-I expression and its relevance for type 1 diabetes - 31 January 2025
Seminario
Laura Baranello – The regulation of DNA topology by supercoiling, topoisomerases and MYC
